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Gold Standard Outcomes

Based on the 7 randomized controlled trials (RCTs) against traditional monopolar TURP, the PK TURP delivers Gold Standard outcomes in terms of changes in all the major endpoints. See Table 1.


Table 1: Primary Outcomes of PK TURP vs Monopolar TURP

PK TURP gives reduced tissue trauma…

Figure 1 Minimal tissue trauma with PK TURP due to lower voltage

…reduced blood loss,

the ability to achieve concomitant hemostasis during resection enabled a reduction to be shown in blood loss (Figure 2).

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Figure 2 Intra-operative blood loss in PK TURP

…reduced physiological change,

PK TURP patients experienced lower drops in Hemoglobin (Hb) and hematocrit (Hct) (Figure 3).

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Figure 3 Hemoglobin & hematocrit change in PK TURP

…reduced continuous bladder irrigation (CBI),

With more effective hemostasis there was less requirement for CBI (Figure 4).

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Figure 4 Continuous bladder irrigation in PK TURP

…reduced length of stay (LOS) and catheterization time,

Despite use of pre-determined protocols for removal of catheter and LOS, both these parameters showed at least one-day reduction when PK TURP is performed. The literature indicates that day case protocols are increasingly being implemented for up to 85–95% 15,33,34,49 of patients with PK TURP.

…reduced complications.

The effect of this less-traumatic PK TURP technique is a reduction in patient complications. TUR syndrome was proven to occur in 1.9% cases in monopolar TURP compared to no cases reported with PK TURP (p<0.001).

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Figure 5 Elimination of TUR Syndrome in PK TURP

Overall patient complication rates were significantly lower for PK TURP (11.0%) compared to monopolar TURP (18.3%) (p<0.001) (Figure 6).

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Figure 6: Overall Patient Complication Rates : PK TURP vs Monopolar TURP.

 


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